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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1932 1
1957 1
1958 1
1959 1
1961 2
1962 2
1963 1
1964 4
1965 3
1966 5
1967 3
1968 7
1969 3
1970 10
1971 3
1972 6
1973 4
1974 10
1975 21
1976 16
1977 14
1978 15
1979 19
1980 24
1981 13
1982 20
1983 20
1984 20
1985 24
1986 25
1987 25
1988 30
1989 31
1990 35
1991 38
1992 36
1993 57
1994 42
1995 42
1996 60
1997 40
1998 49
1999 41
2000 55
2001 56
2002 50
2003 59
2004 54
2005 66
2006 63
2007 63
2008 79
2009 73
2010 100
2011 93
2012 98
2013 101
2014 121
2015 134
2016 122
2017 150
2018 176
2019 183
2020 208
2021 238
2022 227
2023 247
2024 97

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3,372 results

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Page 1
Sodium bicarbonate therapy for patients with severe metabolic acidaemia in the intensive care unit (BICAR-ICU): a multicentre, open-label, randomised controlled, phase 3 trial.
Jaber S, Paugam C, Futier E, Lefrant JY, Lasocki S, Lescot T, Pottecher J, Demoule A, Ferrandière M, Asehnoune K, Dellamonica J, Velly L, Abback PS, de Jong A, Brunot V, Belafia F, Roquilly A, Chanques G, Muller L, Constantin JM, Bertet H, Klouche K, Molinari N, Jung B; BICAR-ICU Study Group. Jaber S, et al. Lancet. 2018 Jul 7;392(10141):31-40. doi: 10.1016/S0140-6736(18)31080-8. Epub 2018 Jun 14. Lancet. 2018. PMID: 29910040 Free article. Clinical Trial.
Randomisation criteria were stratified among three prespecified strata: age, sepsis status, and the Acute Kidney Injury Network (AKIN) score. The primary outcome was a composite of death from any cause by day 28 and the presence of at least one organ failure at day 7. ...I …
Randomisation criteria were stratified among three prespecified strata: age, sepsis status, and the Acute Kidney Injury Network (AKIN) score …
Metabolic acidosis: pathophysiology, diagnosis and management.
Kraut JA, Madias NE. Kraut JA, et al. Nat Rev Nephrol. 2010 May;6(5):274-85. doi: 10.1038/nrneph.2010.33. Epub 2010 Mar 23. Nat Rev Nephrol. 2010. PMID: 20308999 Review.
Metabolic acidosis is characterized by a primary reduction in serum bicarbonate (HCO(3)(-)) concentration, a secondary decrease in the arterial partial pressure of carbon dioxide (PaCO(2)) of approximately 1 mmHg for every 1 mmol/l fall in serum HCO(3)(-) concentrat …
Metabolic acidosis is characterized by a primary reduction in serum bicarbonate (HCO(3)(-)) concentration, a secondary decreas …
Renal Tubular Acidosis.
Bagga A, Sinha A. Bagga A, et al. Indian J Pediatr. 2020 Sep;87(9):733-744. doi: 10.1007/s12098-020-03318-8. Epub 2020 Jun 26. Indian J Pediatr. 2020. PMID: 32591997 Review.
Renal tubular acidosis (RTA) comprises a group of disorders characterized by low capacity for net acid excretion and persistent hyperchloremic metabolic acidosis, despite preserved glomerular filtration rate. ...Diagnosis requires careful evaluation, including exclu …
Renal tubular acidosis (RTA) comprises a group of disorders characterized by low capacity for net acid excretion and persistent hyper …
Hyperchloremic normal gap metabolic acidosis.
Palmer BF, Clegg DJ. Palmer BF, et al. Minerva Endocrinol. 2019 Dec;44(4):363-377. doi: 10.23736/S0391-1977.19.03059-1. Epub 2019 Jul 24. Minerva Endocrinol. 2019. PMID: 31347344 Review.
Extrarenal processes include increased endogenous acid production and accelerated loss of bicarbonate from the body. Metabolic acidosis of renal origin is due to a primary defect in renal acidification with no increase in extrarenal hydrogen ion production. ...In ei …
Extrarenal processes include increased endogenous acid production and accelerated loss of bicarbonate from the body. Metabolic acidosis …
Clinical Effects of Balanced Crystalloids vs Saline in Adults With Diabetic Ketoacidosis: A Subgroup Analysis of Cluster Randomized Clinical Trials.
Self WH, Evans CS, Jenkins CA, Brown RM, Casey JD, Collins SP, Coston TD, Felbinger M, Flemmons LN, Hellervik SM, Lindsell CJ, Liu D, McCoin NS, Niswender KD, Slovis CM, Stollings JL, Wang L, Rice TW, Semler MW; Pragmatic Critical Care Research Group. Self WH, et al. JAMA Netw Open. 2020 Nov 2;3(11):e2024596. doi: 10.1001/jamanetworkopen.2020.24596. JAMA Netw Open. 2020. PMID: 33196806 Free PMC article. Clinical Trial.
IMPORTANCE: Saline (0.9% sodium chloride), the fluid most commonly used to treat diabetic ketoacidosis (DKA), can cause hyperchloremic metabolic acidosis. Balanced crystalloids, an alternative class of fluids for volume expansion, do not cause acidosis and, therefor …
IMPORTANCE: Saline (0.9% sodium chloride), the fluid most commonly used to treat diabetic ketoacidosis (DKA), can cause hyperchloremic metab …
Distal renal tubular acidosis: a systematic approach from diagnosis to treatment.
Giglio S, Montini G, Trepiccione F, Gambaro G, Emma F. Giglio S, et al. J Nephrol. 2021 Dec;34(6):2073-2083. doi: 10.1007/s40620-021-01032-y. Epub 2021 Mar 26. J Nephrol. 2021. PMID: 33770395 Free PMC article. Review.
Renal tubular acidosis (RTA) comprises a group of disorders in which excretion of hydrogen ions or reabsorption of filtered HCO(3) is impaired, leading to chronic metabolic acidosis with normal anion gap. ...The primary or inherited form of dRTA is mostly dia …
Renal tubular acidosis (RTA) comprises a group of disorders in which excretion of hydrogen ions or reabsorption of filtered HCO(3) is …
[Record-Breaking Acidosis].
Kuster MR, Studhalter M, Kindler RM. Kuster MR, et al. Praxis (Bern 1994). 2022 Aug;111(10):576-579. doi: 10.1024/1661-8157/a003879. Praxis (Bern 1994). 2022. PMID: 35920013 German.
Record-Breaking Acidosis Abstract. To maintain a stable cellular metabolism, tight regulation of blood pH within a normal range (pH 7,35-7,45) is essential. ...
Record-Breaking Acidosis Abstract. To maintain a stable cellular metabolism, tight regulation of blood pH within a normal range (pH 7 …
Balanced electrolyte solutions versus isotonic saline in adult patients with diabetic ketoacidosis: A systematic review and meta-analysis.
Catahay JA, Polintan ET, Casimiro M, Notarte KI, Velasco JV, Ver AT, Pastrana A, Macaranas I, Patarroyo-Aponte G, Lo KB. Catahay JA, et al. Heart Lung. 2022 Jul-Aug;54:74-79. doi: 10.1016/j.hrtlng.2022.03.014. Epub 2022 Mar 28. Heart Lung. 2022. PMID: 35358905 Review.
However, balanced electrolyte solutions (BES) have been proposed as an alternative due to a lower propensity to cause hyperchloremic metabolic acidosis. Evidence regarding the use of BES in DKA remains limited. ...METHODS: The study involves a comprehensive search of liter …
However, balanced electrolyte solutions (BES) have been proposed as an alternative due to a lower propensity to cause hyperchloremic metabol …
Renal tubular acidosis.
Santos F, Gil-Peña H, Alvarez-Alvarez S. Santos F, et al. Curr Opin Pediatr. 2017 Apr;29(2):206-210. doi: 10.1097/MOP.0000000000000460. Curr Opin Pediatr. 2017. PMID: 28092281 Review.
PURPOSE OF REVIEW: To facilitate the understanding and knowledge of renal tubular acidosis by providing a summarized information on the known clinical and biochemical characteristics of this group of diseases, by updating the genetic and molecular bases of the primary …
PURPOSE OF REVIEW: To facilitate the understanding and knowledge of renal tubular acidosis by providing a summarized information on t …
Near-drowning.
Neal JM. Neal JM. J Emerg Med. 1985;3(1):41-52. doi: 10.1016/0736-4679(85)90219-7. J Emerg Med. 1985. PMID: 3912425 Review.
Major factors prolonging survival are an age of less than 2 years and immersion in cold water (less than 20 degrees C). Hypoxia and acidosis are the primary physiological derangements, and treatment must be directed toward their correction. ...
Major factors prolonging survival are an age of less than 2 years and immersion in cold water (less than 20 degrees C). Hypoxia and acido …
3,372 results